The Molecular Cell Engineering Laboratory (MCEL) uses the tools of biomolecular engineering, synthetic biology, and systems biology for two purposes:

1) to elucidate fundamental biological design principles that underlie molecular and cellular information processing, and

2) to design new molecular and cellular therapeutics for applications in cancer, diabetes, and infectious diseases.

We couple experimental methods from molecular biology, protein biochemistry, microbiology, and mammalian cell biology with computational modeling and engineering analyses to develop quantitative and predictive frameworks for the biological processes that we interrogate and design.